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Welcome

This is the complete study package for Design and Analysis of Experiments (STS-203) together with Section A of STS-206, Designs and Analysis of Experiments and Sampling Theory (Conventional). The Foundation course laid out three designs — completely randomised, randomised block, Latin square — and analysed each. This course is about what to do when those three are not enough: when a cell holds several observations, when several factors must be studied at once, when the block is too small to hold every treatment, and when the factor levels are quantities and the question is where the optimum lies.

What is assumed, and where to revise it. The syllabus names its pre-requisite exactly, and all of it is on this site: Beyond that, Linear Algebra and Linear Models, Unit 4 supplies the least squares theory that the non-orthogonal analyses of Unit 1 and the response surface fitting of Unit 4 both rest on. Nothing from either is re-derived here.

Course Objectives

  1. Analysis of experimental data using full factorials, with partial and total confounding.
  2. Analysis of experimental data using one-way and two-way classifications.
  3. To estimate the parameters of a population and to estimate variances.

Course Outcomes

  1. Able to carry out the analysis of data by identifying the appropriate complete or incomplete block design, and the appropriate factorial or fractional factorial design.
  2. Able to apply the analysis of covariance to a data set.
  3. Able to carry out the analysis of data using response surface methodology.

Units in this Course

UNIT 1

Several Observations per Cell, Multiple Comparisons and Covariance

What a second observation per cell buys — a pure error term and a testable interaction; proportional cell frequencies, which keep the design orthogonal, and disproportionate ones, which do not, worked to the point where the naive arithmetic produces a negative sum of squares; Fisher's LSD, Duncan's multiple range and Tukey's HSD with the studentized-range points computed rather than quoted; and the analysis of covariance.

UNIT 2

Factorial Experiments

Begins where the Foundation factorial section stops. The generating form that writes any contrast down without thinking about signs; Yates's algorithm through the three passes of a \(2^{3}\), with the two checks the \(2^{2}\) case is too small to motivate; the variance every effect shares; the \(3^{2}\) factorial split into linear and quadratic single-degree components that add back to the whole; and what a three-factor interaction measures.

UNIT 3

Confounding, Fractional Replication and Incomplete Blocks

Confounding as a trade of one contrast for a smaller block, with the block sum of squares shown to equal the confounded effect's; partial confounding and its relative information; aliasing, defining relations and resolution for the half fraction of \(2^{4}\) and the quarter fraction of \(2^{5}\); split-plot designs and their two error terms; and balanced incomplete blocks, analysed in full with adjusted means and the efficiency factor.

UNIT 4

PBIBD, Lattices, Youden Squares and Response Surfaces

Two associate classes and what regularity buys, verified on the triangular scheme; simple lattices and Youden squares; then response surface methodology — the first-order model, the curvature test that only centre points can provide, the path of steepest ascent, and the central composite design whose rotatability condition \(\alpha = F^{1/4}\) is derived from the design moments and then checked numerically.

PRACTICAL

STS-206 Section A — Conventional

All sixteen prescribed experiments: thirteen worked in the units, plus one-way analysis of covariance worked from scratch on data where the adjustment reverses the ranking of two treatments, the two-way case, and the identification and construction of confounded arrangements in \(2^{3}\), \(2^{4}\) and \(3^{2}\).

REFERENCE

Official Syllabus

The prescribed unit-wise outline for STS-203 and the Section A practical list for STS-206, as printed, with the objectives, outcomes, the stated pre-requisite and the reading list.

How This Course Connects to the Others

What is built hereWhere it is used
Interaction, and the pure error that makes it testable Every factorial analysis; the curvature test of Unit 4; and the reason a two-way table with one observation per cell in the Foundation Unit 1 has to assume additivity
Non-orthogonal analysis by fitting constants The same \(R(A \mid \mu, B)\) reduction as the multiple regression \(t\) statistic in Multivariate Analysis, Unit 2, and the rank-deficient normal equations of Linear Algebra and Linear Models, Unit 4
Contrasts and orthogonal polynomial components Any test aimed at a specific alternative rather than at “some difference”; trend analysis over ordered levels
Confounding and fractional replication Screening designs wherever runs are expensive; the fractional factorial profiles of conjoint analysis in Multivariate Analysis, Unit 4
Incomplete block designs Any comparison where the natural block is smaller than the treatment set — tasting panels, machine positions, litters
Response surface methodology Process optimisation; the quadratic form and its eigenvalues from Linear Algebra, Unit 3 classify the stationary point

Next course in learning order: Econometrics Models & multivariate